Compile Data Set for Download or QSAR
Found 89 of ic50 data for polymerid = 50000095,50001344
TargetRibonucleoside-diphosphate reductase subunit M2(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50198892(3-AP | 3-aminopyridine-2-carboxaldehyde thiosemica...)copy SMILEScopy InChI
Affinity DataIC50: 185nMAssay Description:Inhibition of human RRM2 expressed in Escherichia coli BL21-codon plus(DE3) using [14C]-ADP as substrate after 3 mins by liquid scintillation countin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase subunit M2(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50051772((Z)-N'-(5-amino-6-formylpyridin-2-yl)carbamohydraz...)copy SMILEScopy InChI
Affinity DataIC50: 820nMAssay Description:Inhibitory activity against CDP reductase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6QN9PubMed
TargetRibonucleoside-diphosphate reductase subunit M2(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50051768((1Z,N'E)-N'-((3-(methylamino)pyridin-2-yl)methylen...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against CDP reductase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6QN9PubMed
TargetRibonucleoside-diphosphate reductase subunit M2(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50051776((1Z,N'E)-N'-((5-(ethylamino)pyridin-2-yl)methylene...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against CDP reductase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6QN9PubMed
TargetRibonucleoside-diphosphate reductase subunit M2(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50051769((1Z,N'E)-N'-((5-(methylamino)pyridin-2-yl)methylen...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against CDP reductase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6QN9PubMed
TargetRibonucleoside-diphosphate reductase subunit M2(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50051767((1Z,N'E)-N'-((5-(propylamino)pyridin-2-yl)methylen...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against CDP reductase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6QN9PubMed
TargetRibonucleoside-diphosphate reductase subunit M2(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50051775((1Z,N'E)-N'-((5-(allylamino)pyridin-2-yl)methylene...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against CDP reductase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6QN9PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50000150(CHEMBL440253 | Ribonucleotide reductase inhibiting...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory concentration against HSV-1 ribonucleotide reductase R1 protein bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JB2PubMed
TargetRibonucleoside-diphosphate reductase subunit M2(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50051774((1Z,N'E)-N'-((3-(allylamino)pyridin-2-yl)methylene...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against CDP reductase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6QN9PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50000141(2-{2-[2-(2-{2-[2-(2-{2-[2-Acetylamino-3-(1H-indol-...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory concentration against HSV-1 ribonucleotide reductase R1 protein bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JB2PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50000153(CHEMBL386066 | Ribonucleotide reductase inhibiting...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory concentaration against HSV-1 ribonucleotide reductase R1 protein bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JB2PubMed
TargetRibonucleoside-diphosphate reductase subunit M2(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50051766((1Z,N'E)-N'-((5-(butylamino)pyridin-2-yl)methylene...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory activity against CDP reductase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6QN9PubMed
TargetRibonucleoside-diphosphate reductase subunit M2(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50051777((1Z,N'E)-N'-((5-(aminomethyl)pyridin-2-yl)methylen...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory activity against CDP reductase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6QN9PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50000152(CHEMBL277280 | Ribonucleotide reductase inhibiting...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibitory concentaration against HSV-1 ribonucleotide reductase R1 protein bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JB2PubMed
TargetRibonucleoside-diphosphate reductase subunit M2(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50051773((Z)-N'-(3-amino-6-formylpyridin-2-yl)carbamohydraz...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory activity against CDP reductase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6QN9PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50000146(CHEMBL414299 | Ribonucleotide reductase inhibiting...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory concentration against HSV-1 ribonucleotide reductase R1 protein bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JB2PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50000165(CHEMBL437817 | Ribonucleotide reductase inhibiting...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory concentaration against HSV-1 ribonucleotide reductase R1 protein bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JB2PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50000154(2-{2-[2-(2-{2-[2-(2-{2-[2-Acetylamino-3-(4-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory concentaration against HSV-1 ribonucleotide reductase R1 protein bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JB2PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50000149(CHEMBL261954 | Ribonucleotide reductase inhibiting...)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibitory concentaration against HSV-1 ribonucleotide reductase R1 protein bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JB2PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50000166(2-{2-[2-(2-{2-[2-(2-{2-[2-Acetylamino-3-(4-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibitory concentaration against HSV-1 ribonucleotide reductase R1 protein bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JB2PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50000163(CHEMBL386716 | Ribonucleotide reductase inhibiting...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibitory concentaration against HSV-1 ribonucleotide reductase R1 protein bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JB2PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50000164(CHEMBL405583 | Ribonucleotide reductase inhibiting...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibitory concentaration against HSV-1 ribonucleotide reductase R1 protein bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JB2PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50000157(CHEMBL261962 | Ribonucleotide reductase inhibiting...)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibitory concentration against HSV-1 ribonucleotide reductase R1 protein bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JB2PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50000137(CHEMBL263845 | Ribonucleotide reductase inhibiting...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibitory concentaration against HSV-1 ribonucleotide reductase R1 protein bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JB2PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50000145(CHEMBL386344 | Ribonucleotide reductase inhibiting...)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibitory concentaration against HSV-1 ribonucleotide reductase R1 protein bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JB2PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50247442(CHEMBL3193213)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50000148(2-{2-[2-(2-{2-[2-(2-{2-[2-Acetylamino-3-(4-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibitory concentaration against HSV-1 ribonucleotide reductase R1 protein bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JB2PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50000134(2-{2-[2-(2-{2-[2-(2-{2-[2-Acetylamino-3-(4-chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibitory concentration against HSV-1 ribonucleotide reductase R1 protein bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JB2PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50247435(CHEMBL4073197)copy SMILEScopy InChI
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50247434(CHEMBL1958235)copy SMILEScopy InChI
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50247436(CHEMBL4100050)copy SMILEScopy InChI
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50000159(CHEMBL331824 | Ribonucleotide reductase inhibiting...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibitory concentration against HSV-1 ribonucleotide reductase R1 protein bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JB2PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50000151(2-{2-[2-(2-{2-[2-(2-{2-[2-Acetylamino-3-(4-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibitory concentaration against HSV-1 ribonucleotide reductase R1 protein bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JB2PubMed
TargetRibonucleoside-diphosphate reductase subunit M2(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50051771((1Z,N'E)-N'-((3,5-diaminopyridin-2-yl)methylene)ca...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibitory activity against CDP reductase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6QN9PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50247408(CHEMBL4067105)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50247441(CHEMBL4067759)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase subunit M2(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50051770((1Z,N'E)-N'-((5-amino-4-(morpholinomethyl)pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory activity against CDP reductase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6QN9PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50000161(2-[2-(2-{2-[2-(2-{2-[2-(2-Acetylamino-3-cyclohexyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibitory concentaration against HSV-1 ribonucleotide reductase R1 protein bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JB2PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50000138(CHEMBL384014 | Ribonucleotide reductase inhibiting...)copy SMILEScopy InChI
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibitory concentration against HSV-1 ribonucleotide reductase R1 protein bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JB2PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50247433(CHEMBL4059739)copy SMILEScopy InChI
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50000162(CHEMBL263439 | Ribonucleotide reductase inhibiting...)copy SMILEScopy InChI
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibitory concentration against HSV-1 ribonucleotide reductase R1 protein bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JB2PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50000155(CHEMBL265013 | Ribonucleotide reductase inhibiting...)copy SMILEScopy InChI
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibitory concentaration against HSV-1 ribonucleotide reductase R1 protein bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JB2PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50247432(CHEMBL4077024)copy SMILEScopy InChI
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50247427(CHEMBL4064659)copy SMILEScopy InChI
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50247440(CHEMBL4091609)copy SMILEScopy InChI
Affinity DataIC50: 2.07E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50247426(CHEMBL4097201)copy SMILEScopy InChI
Affinity DataIC50: 2.11E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50247424(CHEMBL4101599)copy SMILEScopy InChI
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50500167(CHEMBL3747291)copy SMILEScopy InChI
Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2M5MPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50500166(CHEMBL3747319)copy SMILEScopy InChI
Affinity DataIC50: 2.36E+4nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2M5MPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Notre-Dame Hospital Research

Curated by ChEMBL
LigandPNGBDBM50247425(CHEMBL4070699)copy SMILEScopy InChI
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
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